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What does prescribing off label mean? Off - label prescribing is when a physician gives you a drug that the U.S. Food and Drug Administration (FDA) has approved to treat a condition different than your condition. This practice is legal and common. Understanding Investigational Drugs and Off Label Use of Approved Drugs. Off - Label Drug Use in Cancer Treatment.
What are the signs and symptoms of nephrotoxicity? Symptoms Decreased urine output, although occasionally urine output remains normal. Fluid retention, causing swelling in your legs, ankles or feet. Shortness of breath. Fatigue. Confusion. Nausea. Weakness. Irregular heartbeat.